DARPA just opened up a new BAA for the Epigenetic CHaracterization and Observation program. The program is looking to identify and discriminate epigenetic signatures created by exposure to threat agents; and to create technology that performs highly specific forensic and diagnostic analyses to reveal the exact type and time of exposure. To develop this capability, researchers will have to assemble a foundational training dataset of pre- and post-exposure epigenetic readouts in biological samples. They will also have to create a device capable of performing multiple molecular analyses and onboard bioinformatics in 30 minutes or less, compared to an average of two days using current lab-centered processes. If you think you have a novel approach towards detecting these type of changes apply! The identification of radiation damage after the fact has always been difficult, getting all types of exposures could be very useful.
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